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標題:
羅啟文
兼任助理教授
高雄醫學大學附設中和紀念醫院/外科部/乳房外科
淡江大學水資源及環境工程所博士
【研究專長】
細胞生物學、生物技術、細胞治療、細胞及微生物培養與動物試驗
1.國科會計畫審查委員
2.國際期刊[Pharmaceuticals SCIE/Impact Factor: 5.215]客座編輯委員
3.2022高雄國際癌症研討會(2021 Kaohsiung International Cancer Symposium)受邀講者
4.2021高雄國際癌症研討會(2021 Kaohsiung International Cancer Symposium)受邀講者
5.2020台北國際乳癌研討會(2020 Taipei International Breast Cancer Symposium) 優秀論文獎
6.2019高雄國際癌症研討會(2019 Kaohsiung International Cancer Symposium)優秀海報獎
1.探討細胞因子誘導的殺手細胞(CIK)合併FAK抑制劑對三陰性乳癌治療的可行性(109-2314-B-037-036-MY3)-科技部計畫 (主持人)
2.探討粘著斑激酶作為腫瘤微環境中流體應力的調控因子與轉移性乳癌治療標靶可行性(108-2314-B-037-033-)-科技部計畫 (主持人)
【期刊論文】
1. Wang HC, Luo CW, Chen TY, Chen YZ, Fang SY, Lai CY, Hung WC, Wu CC, Chen LT, Liu YC, Pan MR (2022). Skp2-mediated Zeb1 expression facilitates cancer migration by a ubiquitination-independent pathway. Life Sciences, Volume 311, Part A, 121135.
2. Chin CC, Shiau JP, Luo CW, Hou MF (2022). Lymphangioma of small bowel in adults: A rare cause of abdominal symptoms. Asian Journal of Surgery.
3. Lung JH, Hung MS, Wang TY, Chen KL, Luo CW, Jiang YY, Wu SY, Lee LW, Lin PY, Chen FF, Liao HF, Lin YC (2022). Lipid Droplets in Lung Cancers Are Crucial for the Cell Growth and Starvation Survival. Int. J. Mol. Sci., 2022, 23(20), 12533.
4. Chang SJ, Bin PJ, Luo CW, Chai CY (2022). CHD4 plays a critical role in arsenite-induced oxidative damage in human urothelial carcinoma. Pathology - Research and Practice, 240:154173.
5. Wang HC, Shih HY, Wu CC, Chen LT, Luo CW, Liu YC, Du JS, Huang MC, Su YY, Chen HD, Hsiao HH, Moi SH, Pan MR (2022). Clustering of Chromatin Remodeling Enzymes Predicts Prognosis and Clinical Benefit of Therapeutic Strategy in Pancreatic Cancer. Int J Med Sci., 19(10):1615-1627.
6. Sung PS, Yang CC, Chiang JY, Chen CH, Luo CW*, Yip HK (2022). Inhibition of histone methyltransferase G9a effectively protected the kidney against ischemia-reperfusion injury. Am J Transl Res, 14(6):3683-3697.
7. Chin CC, Shiau JP, Luo CW, Hou MF (2022). Unilateral lower-limb vasculopathy: A rare adverse event of CDK4/6 inhibitor in breast cancer. Kaohsiung J Med Sci.
8. Ou-Yang F, Li CL, Chen CC, Shen YC, Moi SH, Luo CW, Xia W, Wang YN, Lee HH, Wang LH, Wang SC, Pan MR, Hou MF, Hung MC (2022). De-glycosylated membrane PD-L1 in tumor tissues as a biomarker for responsiveness to atezolizumab (Tecentriq) in advanced breast cancer patients. Am J Can Res, 12(1):123-137.
9. Shiau JP, Wu CC, Chang SJ, Pan MR, Liu WT, Ou-Yang F, Chen FM, Hou MF, Shih SL, Luo CW* (2021). FAK Regulates VEGFR2 Expression and Promotes Angiogenesis in Triple-Negative Breast Cancer. Biomedicines, 9(12), 1789.
10. Kao CN, Moi SH, Hou MF, Luo CW, Chen FM, Pan MR (2021). RNF8–CDH1 Co-Expression Predicts Clinical Benefit of Chemoradiotherapy in Triple-Negative Breast Cancer. J. Pers. Med., 11(7), 655.
11. Chang CL, Huang CR, Chang SJ, Wu CC, Chen HH, Luo CW*, Yip HK (2021). CHD4 as an important mediator in regulating the malignant behaviors of colorectal cancer. Int. J. Biol. Sci., Int J Biol Sci 2021; 17(7):1660-1670.
12. Wang HC, Chan LP, Wu CC, Chang SJ, Moi SH, CW Luo CW, Pan MR (2021). Silencing DNA Polymerase β Induces Aneuploidy as a Biomarker of Poor Prognosis in Oral Squamous Cell Cancer. Int J Mol Sci, 22(5):2402.
13. Luo CW, Hou MF, Huang CW, Wu CC, Ou-Yang F, Li QL, Wu CC, Pan MR (2020). The CDK6-c-Jun-Sp1-MMP-2 axis as a biomarker and therapeutic target for triple-negative breast cancer. Am J Can Res, 10(12):4325-4341.
14. Chang TI, Hsu KH, Li SJ, Chuang MK, Luo CW, Chen YJ, Chang CI (2020). Evolution of pulmonary valve reconstruction with focused review of expanded polytetrafluoroethylene handmade valves. Interact Cardiovasc Thorac Surg, ivaa302.
15. Huang WL, Luo CW, Chou CL, Yang CC, Chen TJ, Li CF, Pan MR (2020). High Expression of UBE2B as a Poor Prognosis Factor in Patients with Rectal Cancer Following Chemoradiotherapy. Anticancer Res., 40(11):6305-6317.
16. Li CL, Huang CW, Ko CJ, Fang SY, Ou-Yang F, Pan MR, Luo CW*, Hou MF (2020). Curcumol Suppresses Triple-negative Breast Cancer Metastasis by Attenuating Anoikis Resistance via Inhibition of Skp2-mediated Transcriptional Addiction. Anticancer Research, 40(10):5529-5538.
17. Sung PH, Lin KC, Chai HT, Chiang JY, Shao PL, Luo CW, Yip HK (2020). Losing Regulation of the Extracellular Matrix is Strongly Predictive of Unfavorable Prognostic Outcome after Acute Myocardial Infarction. Int J Mol Sci., 21(17): E6219.
18. Chen YT, Huang CR, Chang CL, Chiang JY, Luo CW, Chen HH, Yip HK (2020). Jagged2 progressively increased expression from Stage I to III of Bladder Cancer and Melatonin-mediated downregulation of Notch/Jagged2 suppresses the Bladder Tumorigenesis via inhibiting PI3K/AKT/mTOR/MMPs signaling. Int J Biol Sci., 16(14):2648-2662.
19. Sung PH#, Luo CW#, Chiang JY, Yip HK (2020). The combination of G9a histone methyltransferase inhibitors with erythropoietin protects heart against damage from acute myocardial infarction. American Journal of Translational Research, 12(7):3255-3271.
20. Hsu YC, Luo CW, Huang WL, Wu CC, Chou CL, Chen CI, Chang SJ, Chai CY, Wang HC, Chen TY, Li CF, Pan MR (2020). BMI1-KLF4 Axis Deficiency Improves Responses to Neoadjuvant Concurrent Chemoradiotherapy in Patients With Rectal Cancer. Radiother Oncol., 149:249-258.
21. Chang SY, Tu HP, Lai YC, Luo CW, Nejo T, Tanaka S, Chai CY, Kwan AL (2020). Increased Vascular Adhesion Protein 1 (VAP-1) Levels are Associated with Alternative M2 Macrophage Activation and Poor Prognosis for Human Gliomas. Diagnostics, Diagnostics 2020, 10(5), 256.
22. Chang TI, Hsu KH, Luo CW, Yen JH, Lu PC, Chang CI (2020). In vitro study of trileaflet polytetrafluoroethylene conduit and its valve-in-valve transformation. Interact Cardiovasc Thorac Surg.
【研討會論文】
1. Targeting focal adhesion kinase as an alternative antiangiogenetic therapy in triple-negative breast cancer, 2021 Kaohsiung International Cancer Symposium
2. Efficacy of cytokine-induced killer (CIK) cells in combination with FAK inhibitor for triple-negative breast cancer, , 2020 Kaohsiung International Cancer Symposium
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