師資陣容

特聘教授

特聘教授兼美粧生技產品開發暨功能性評估中心主任

高雄醫學大學/醫學研究所/博士

【研究專長】
◎化粧品開發與應用研究
◎細胞、微生物培養與動物試驗
◎人類皮膚癌抑癌作用的分子機轉探討
◎奈米脂質體製劑應用及經皮效能評估之研究
◎中草藥及海洋生物萃取物及產品之刺激性及功效性評估
◎微脂粒包覆美白、抗氧化與細胞修復化粧品功效性與穩定性評估

◎化粧品安全評估人員
◎行政院衛生署醫事檢驗師
◎化粧品安全評估人員證照
◎實驗室認證規範ISO/IEC 17025證照
◎乙級及丙級美容技術士證
◎國際芳療師證照
◎生技化粧品美容保養專業經理人

◎擔任 經濟部工業局 自願性化粧品優良製造規範驗證審查(GMP) 查核委員
◎擔任 財團法人醫藥工業技術發展中心 MIT微笑標章審查單位 審查委員
◎擔任 衛生福利部食品藥物管理署 化粧品衛生管理諮議會委員
◎擔任 行政院公共工程委員會 專家學者
◎擔任 財團法人金屬工業研究發展中心 顧問
◎擔任 中華民國農科園區產業協會 屏東農業生物科技園區 輔導專家
◎擔任 中華民國芳香精油美容保健發展協會 榮譽理事與顧問
◎榮獲 2011-2025年 嘉南藥理大學 產學合作特優/優良/傑出教師獎
◎榮獲 2025 IIIC國際創新發明競賽 金牌獎
◎榮獲 2025台灣創新技術博覽會發明競賽 銅牌獎
◎榮獲 2024年綠點子國際發明暨設計競賽特別獎-發明類社會組 鈦金獎
◎榮獲 2024年綠點子國際發明暨設計競賽特別獎-發明類社會組 鈦金獎
◎榮獲 2024年綠點子國際發明暨設計競賽特別獎-評審團特別獎 最佳原住民護膚產品獎
◎榮獲 2023年「2023美麗時光三十載，躍進未來國際研討會」 第一名
◎榮獲 2023年第七屆全國暨國際形象美學創意設計競賽 創意化妝品調製商品設計B組 第三名
◎榮獲 2023台灣創新技術博覽會發明競賽 金牌獎
◎榮獲 2022美粧產學論壇暨永續發展國際研討會 美粧產品研發、檢驗、製造與綠色永續性主題組 第三名
◎榮獲 2022年綠點子國際發明暨設計競賽 肽金獎
◎榮獲 2022年SMILE UP嘉誠微笑盃創新實驗室配方設計競賽 第二名
◎榮獲 2022年全國美容科學研討會 第一名
◎榮獲 2022年精油調理美學與生活應用競賽 第一名
◎榮獲 2021年 IIIC國際創新發明競賽 金牌獎
◎榮獲 2021年台灣創新技術博覽會發明競賽 銅牌獎
◎榮獲 2020年台灣創新技術博覽會發明競賽 銀牌獎

[近5年科技部一般專題研究計畫]
◎植萃外泌體及其microRNA於光損傷修復機制與皮膚調節劑之開發應用 2024/06/01~2027/07/31 主持人 4,140,000元
◎單萜糖苷於氧化壓力及光損傷之修復能力與其合併皮膚癌藥物之化學預防機制探討 2017/08/01~2020/07/31 主持人 3,600,000元
◎單萜糖苷於氧化壓力及光損傷之修復能力與其合併皮膚癌藥物之化學預防機制探討 2017/08/01~2020/07/31 主持人 3,600,000元

[近5年科技部優秀年輕學者研究計畫]
◎山酮素類作為MTH1抑制劑於皮膚氧化DNA損傷修護及抑癌之機制探討(3/3) 2022/08/01~2023/07/31 主持人 1,920,000元
◎山酮素類作為MTH1抑制劑於皮膚氧化DNA損傷修護及抑癌之機制探討(2/3) 2021/08/01~2022/07/31 主持人 1,500,000元
[科技部優秀年輕學者研究計畫]
◎山酮素類作為MTH1抑制劑於皮膚氧化DNA損傷修護及抑癌之機制探討(1/3) 2020/08/01~2021/07/31 主持人 1,820,000元

[近5年科技部產學合作研究計畫]
◎油甘果外泌體樣奈米微囊及其miRNA於抗刺激功能產品之開發應用 2025/06/01∼2026/05/31 主持人
◎油甘果外泌體樣奈米微囊及其miRNA於抗刺激功能產品之開發應用 2025/06/01∼2026/05/31 主持人
◎創新台灣蘭花芽胚外泌體樣奈米囊泡於頭皮養護產品之開發與應用2024/06/01∼2025/05/31 主持人
◎台灣熟地黃多功能奈米液胞產品用於敏感性眼周肌膚之開發與應用2023/06/01∼2024/05/31 主持人
◎用於頭頸部放射性皮膚炎之功效性植萃凝膠微乳體產品開發與應用 2022/06/01∼2023/05/31 主持人
◎鎮膚抗敏性植萃奈米液胞產品開發與評估計畫 2021/06/01∼2022/05/31 主持人
◎營養烏髮健髮奈米髮品之開發與評估 2020/06/01∼2021/05/31 主持人
◎機能性眼部抗皺奈米保養品之開發與評估 2019/06/01∼2020/05/31 主持人

[近5年產學合作計畫]
◎大江生醫生物技術(上海)有限公司/維他命C補充品之功效性檢測計畫/2025/10/08~2026/10/31
◎台灣美王國際有限公司/化粧品之微生物品保檢測計畫II/2025/09/01~2026/08/31
◎綠茵生技股份有限公司/BeauSaki tm 燕窩胜肽產品之功效性評估/2025/08/01~2026/07/31
◎德典生技股份有限公司/再生奇蹟膠原精華產品之功效性檢測計畫/2025/03/01~2026/02/28
◎Puredia Corporation Limited/CyanthOxTM Hard Capsule臨床研究計畫/2025/03/01~2027/02/28
◎新普利股份有限公司/膠原飲品之美肌功效性評估/2025/01/01~2025/12/31
◎使之覺醒生化科技有限公司/御光淨白煥采油之肌膚功效性測試計畫/2025/01/01~2025/12/31
◎達爾膚生醫科技股份有限公司/DR.WU瞬適膚舒緩修護潤澤霜之肌膚刺激性測試/2024/11/01~2025/11/30
◎百岳特生物技術(上海)有限公司/葡萄膠原飲之美肌功效性評估/2024/06/15~2025/06/30
◎汩宇國際有限公司/HH EPR2抗痘精華與卸妝油之肌膚功效評估/2024/01/01~2024/12/31
◎洸鼎生物科技有限公司/DR.HSIEH胜肽精華產品於肌膚機能性測試計畫/2024/01/01~2025/01/11
◎中家國際有限公司/中藥粉之萃取液製備與效能測試/2023/12/01~2024/05/31
◎明基材料股份有限公司/護妍天使三重酸煥膚極效精華於肌膚功效檢測計畫/2023/09/07~2024/08/30
◎晶碩光學股份有限公司/AQUAMAX肌能賦活系列日夜精華及眼霜產品於肌膚改善功效檢測計畫/2023/07/01~2024/07/31
◎絨紫生技股份有限公司/馬尾藻微乳噴霧產品於強韌頭髮效能驗證計畫/2022/03/01~2022/09/30
◎英屬維京群島商沙威隆國際股份有限公司台灣分公司/沙威隆抗菌保濕沐浴乳產品於肌膚保濕功效檢測計畫/2022/02/21~2022/08/31
◎德典生技股份有限公司/杏仁酸瞬效淨痘無瑕精華產品之抑制痤瘡桿菌抗痘效能評估/2021/12/10~2022/05/31
◎大江生醫股份有限公司/香蕉花/TCI999於頭髮及身體保健臨床功效驗證計畫/2021/03/15~2022/03/14
◎達爾膚生醫科技股份有限公司/照光防曬持久力之功效性評估/2020/12/1∼2021/2/28
◎財團法人紡織產業綜合研究所/幾丁質產品之皮膚安全與功效性檢測計畫/2020/9/1∼2021/3/31
◎豐華生物科技股份有限公司/益生菌保養品之檢測計畫/2020/2/1∼2020/8/31
◎阿原工作室股份有限公司/艾草原料開發和組成分析檢測計畫/2019/11/1∼2020/12/31

◎已發表之國際學術論文69篇、已發表之學術研討會論文116篇
◎已獲得之專書2篇
1. Chan LP, Tseng YP, Wang HC, Chien CY, Wu CW, Wang LF, Yen TW, Wang PC, Liaw CC, Liang CH*. The PI3K inhibitor HCD promotes caspase activation in head and neck squamous cells by upregulating the extrinsic and intrinsic apoptosis pathways. J Oral Pathol Med. 2025 Sep 0:1-12.
2. Chan LP and Liang CH*. Natural plant-based rejuvenating compositions: Human study on Astragalus membranaceus and Centella asiatica saponins for skin health. Cosmetics. 2025 Jun 20. IF = 3.2.
3. Chan LP, Cheng DL, Tseng YP, Liang CH*. Halobacteria formula improvement of skin care-A randomized, double-blind, placebo-controlled clinical study. J Cosmet Dermatol. 2025 Feb;24(2):e70011.
4. Chan LP, Yen TW, Tseng YP, Liang CH*. The impact of oral sea-buckthorn oil on skin, blood markers, ocular, and vaginal health: A randomized control trial. J Funct Foods. 2024 Jan 112; 105973.
5. Lin YK, Liang CH, Lin YH, Lin YH, Lin TW, V´azquez JJ, van Campen A, Chiang CF. Oral supplementation of vegan collagen biomimetic has beneficial effects on human skin physiology: A double-blind, placebo-controlled study. J Funct Foods. 2024, 112; 105955.
6. Chan LP, Tseng YP, Wang HC, Chien CY, Wu CW, Wang LF, Liang CH*. Growth regulated oncogene-α upregulates TNF-α and COX-2 and activates NOD1/RIPK2 mediated-MAPK pathway in head and neck squamous cell carcinoma. J Cancer. 2023 Apr 9;14(6):989-1000.
7. Liang CH, Lin YH, Lin YK, Chiang CF*. Hair growth-promotion effects and antioxidant activity of the banana flower extract HappyAngel®: double-blind, placebo-controlled trial. Food Sci Hum Wellness 2023, Sep 12; 1917-23.
8. Ho HH, Chen CW, Yi TH, Huang YF, Kuo YW, Lin JH, Chen JF, Tsai SY, Chan LP, Liang CH*. Novel application of a co-fermented postbiotics of TYCA06/AP-32/CP-9/collagen in the improvement of acne vulgaris-A randomized clinical study of efficacy evaluation. J Cosmet Dermatol. 2022 Nov;21(11):6249-6260.
9. Chan LP, Tseng YP, Wang HC, Chien CY, Wu CW, Wang LF, Liang CH*. Growth regulated oncogene-α contribute to EMT/MMPs pathway by binding its receptors in head and neck squamous cell carcinoma. Life Sci. 2022 Oct 1;306:120791.
10. Tsai TY, Lin RJ, Liu C, Tseng YP, Chan LP, Liang CH*. Djulis supplementation against oxidative stress and ultraviolet radiation-induced cell damage: The influence of antioxidant status and aging of skin in healthy subjects. J Cosmet Dermatol. 2022 Jul;21(7):2945-2953.
11. Liu C, Tseng YP, Chan LP, Liang CH*. The potential of Streptococcus thermophiles (TCI633) in the anti-aging. J Cosmet Dermatol. 2022 Jun;21(6):2635-2647.
12. Kuan CM, Liang CH, Chuang WH, Lin TY, Hsu PK. Ameliorating effect of Crassocephalum rabens (Asteraceae) extract on skin aging: A randomized, parallel, double-blind, and placebo-controlled study. Nutrients. 2022, Jun; 27;14(13):2655.
13. Chan LP, Tseng YP, Liu C, Liang CH*. Fermented pomegranate extracts protect against oxidative stress and aging of skin. J Cosmet Dermatol. 2022 May;21(5):2236-2245.
14. Tseng YP, Liu C, Chan LP, Liang CH*. Coffee pulp supplement affects antioxidant status and favors anti-aging of skin in healthy subjects. J Cosmet Dermatol. 2022 May;21(5):2189-2199.
15. Chan LP, Tseng YP, Liu C, Liang CH*. Anti-oxidant and anti-aging activities of fermented vegetable-fruit drink. J Food Nutr Res. 2021 May;9(5):240-250.
16. Ho HH, Chen CW, Huang YF, Kuo YW, Lin JH, Chen JF, Hsu CH, Yi TH, Chan LP, Liang CH*. The novel use of postbiotics of TYCA06/AP-32/CP-9 in the amelioration of atopic dermatitis and improvement of skin care-A clinical study. Int J Clin Diagn Res. 2021 Mar;9(1):18-28.
17. Chou TH, Nugroho DS, Chang JY, Cheng YS, Liang CH, Deng MJ. Encapsulation and characterization of nanoemulsions based on an anti-oxidative polymeric amphiphile for topical apigenin delivery. Polymers (Basel). 2021, Mar 25;13(7):1016. doi: 10.3390/polym13071016. PMID: 33806031; PMCID: PMC8037426.
18. Chan LP, Tseng YP, Liu C, Liang CH*. Anti-oxidant and anti-aging activities of fermented vegetable-fruit drink. J Food Nutr Res. 2021, May;9(5):240-250.
19. Ho HH, Chen CW, Huang YF, Kuo YW, Lin JH, Chen JF, Hsu CH, Yi TH, Chan LP, Liang CH*. The novel use of postbiotics of TYCA06/AP-32/CP-9 in the amelioration of atopic dermatitis and improvement of skin care-A clinical study. Int J Clin Diagn Res. 2021, Mar;9(1):18-28.
20. Chang HC, Lin YK, Liang CH, Huang HW, Lin YH, Lin YH, Wei-Chun Hu WC, Chiang CF. Collagen formula with Chinese herbal medicine can improve skin condition and reduce inflammation: a double-blind, randomized, placebo-controlled trial. Nutr Food Sci. 2021, Jun;16. doi: 10.1111/jocd.13500. Epub 2020 Jun 12. PMID: 32530124.
21. Shen PT, Chiu SW, Chang JY, Chung TW, Liang CH, Deng MJ, Chou TH*. Formation and characterization of hydrogenated soybean lecithin/TPGS nano-dispersions as a potential carrier for active herbal agents. Colloids Surf A Physicochem Eng Asp. 2021, Feb;611(20):125796.
22. Lin P, Alexander RA, Liang CH, Liu C, Lin YH, Lin YH, Chan LP, Kuan CM. Collagen formula with Djulis for improvement of skin hydration, brightness, texture, crow's feet, and collagen content: A double-blind, randomized, placebo-controlled trial. J Cosmet Dermatol. 2021, Jan;20(1):188-194. doi: 10.1111/jocd.13500. Epub 2020 Jun 12. PMID: 32530124.
23. Wu CS, Wu DY, Wang SS, Chan LP, Liang CH. Modulation of polylactic acid nanofiber containing corn stalk waste via electrospinning: fabrication, characterization, and cytocompatibility. Int J Polym Mater. 2020, Jul 3.
24. Chou TH, Setiyo Nugroho D, Liang CH. Effect of mixed emulsifier on the physicochemical properties of avocado oil nano-emulsions. Int J Chem Eng Appl. 2020, Apr;11(2):57-62.

◎已發表之國際學術論文72篇、已發表之學術研討會論文115篇
◎已獲得之專書2篇
1. Chan LP, Cheng DL, Tseng YP, Liang CH* (2025, Jan). Halobacteria formula improvement of skin care-A randomized, double-blind, placebo-controlled clinical study. J Cosmet Dermatol, 24(1): e1664.
2. Chan LP, Yen TW, Tseng YP, Liang CH* (2024, Jan). The impact of oral seabuckthorn oil on skin, blood markers, ocular, and vaginal health: A randomized control trial. J Funct Foods, 112; 105973.
3. Chan LP, Tseng YP, Wang HC, Chien CY, Wu CW, Wang LF, Liang CH*. (2023, Apr). Growth regulated oncogene-α upregulates TNF-α and COX-2 and activates NOD1/RIPK2 mediated-MAPK pathway in head and neck squamous cell carcinoma. J Cancer, 14, 989-1000.
4. Chan LP, Tseng YP, Wang HC, Chien CY, Wu CW, Wang LF, Liang CH*. (2022, Oct). Growth regulated oncogene-α contribute to EMT/MMPs pathway by binding its receptors in head and neck squamous cell carcinoma.. Life Sci, 1;306:120791.
5. Ho HH, Chen CW, Yi TH, Huang YF, Kuo YW, Lin JH, Chen JF, Tsai SY, Chan LP, Liang CH*. (2022, Jul). Novel application of a co-fermented postbiotics of TYCA06/AP-32/CP-9/collagen in the improvement of acne vulgaris-A randomized clinical study of efficacy evaluation. J Cosmet Dermatol, Jul 11.
6. Tsai TY, Lin RJ, Liu C, Tseng YP, Chan LP, Liang CH* (2022, Jul). Djulis supplementation against oxidative stress and ultraviolet radiation-induced cell damage: The influence of antioxidant status and aging of skin in healthy subjects. J Cosmet Dermatol, 21(7):2945-2953.
7. Kuan CM, Liang CH, Chuang WH, Lin TY, Hsu PK. (2022, Jun). Ameliorating effect of Crassocephalum rabens (Asteraceae) extract on skin aging: A randomized, parallel, double-blind, and placebo-controlled study. Nutrients, 27;14(13):2655.
8. Liu C, Tseng YP, Chan LP, Liang CH* (2022, Jun). The potential of Streptococcus thermophiles (TCI633) in the anti-aging. J Cosmet Dermatol, 21(6):2635-2647.
9. Chan LP, Tseng YP, Liu C, Liang CH* (2022, May). Fermented pomegranate extracts protect against oxidative stress and aging of skin. J Cosmet Dermatol, 21(5):2236-2245.
10. Tseng YP, Liu C, Chan LP, Liang CH* (2022, May). Coffee pulp supplement affects antioxidant status and favors anti-aging of skin in healthy subjects. J Cosmet Dermatol, 21(5):2189-2199.
11. Chang HC, Lin YK, Liang CH, Huang HW, Lin YH, Lin YH, Wei-Chun Hu WC, Chiang CF (2021, Jun). Collagen formula with Chinese herbal medicine can improve skin condition and reduce inflammation: a double-blind, randomized, placebo-controlled trial. Nutrition & Food Science, 16.
12. Chan LP, Tseng YP, Liu C, Liang CH* (2021, May). Anti-oxidant and anti-aging activities of fermented vegetable-fruit drink. J Food Nutr Res, 9(5), 240-250.
13. Chou TH, Nugroho DS, Chang JY, Cheng YS, Liang CH, Deng MJ (2021, Mar). Encapsulation and characterization of nanoemulsions based on an anti-oxidative polymeric amphiphile for topical apigenin delivery. Polymers (Basel), 25;13(7):1016.
14. Ho HH, Chen CW, Huang YF, Kuo YW, Lin JH, Chen JF, Hsu CH, Yi TH, Chan LP*, Liang CH* (2021, Mar). The novel use of postbiotics of TYCA06/AP32/CP-9 in the amelioration of atopic dermatitis and improvement of skin care - A clinical study. Int J Clin Diagn Res, 9(1): 18-28.
15. Shen PT, Chiu SW, Chang JY, Chung TW, Liang CH, Deng MJ, Chou TH (2021, Feb). Formation and characterization of hydrogenated soybean lecithin/TPGS nano-dispersions as a potential carrier for active herbal agents. Colloids Surf A Physicochem Eng Asp, 611(20):125796.
16. Lin P, Alexander RA, Liang CH, Liu C, Lin YH, Lin YH, Chan LP, Kuan CM (2021, Jan). Collagen formula with Djulis for improvement of skin hydration, brightness, texture, crow's feet, and collagen content: A double-blind, randomized, placebo-controlled trial. J Cosmet Dermatol, 20(1):188-94.
17. Wu CS, Wu DY, Wang SS, Chan LP, Liang CH (2020, Jul). Modulation of polylactic acid nanofiber containing corn stalk waste via electrospinning: fabrication, characterization, and cytocompatibility. Int J Polym Mater, Jul 3.
18. Chou TH, Setiyo Nugroho D, Liang CH* (2020, Apr). Effect of mixed emulsifier on the physicochemical properties of avocado oil nano-emulsions. Int J Chem Eng Appl, 11(2):57-62.
19. Liu C, Chan LP , Liang CH* (2019, Dec). The anti-aging activities against oxidative damages of Rosa roxburghii and multi-fruit concentrate drink. J Food Nutr Res, 7(12), 845-850.
20. Chan LP, Tseng YP, Ding HY, Pan SM, Chiang FY, Wang LF, Chou TH, Lien PJ, Liu C, Kuo PL, Liang CH* (2019, Oct). Tris(8-Hydroxyquinoline)iron induces apoptotic cell death via oxidative stress and by activating death receptor signaling pathway in human head and neck carcinoma cells. Phytomedicine, 63:153005.

專利及技轉：
◎已獲得之專利48件，大陸專利17件，澳洲專利1件，紐西蘭專利1件
◎技轉20件